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Colosseum
The largest amphitheatre ever built in antiquity once held around 50,000 spectators for gladiator fights and animal hunts; a visit to the underground passages shows the elevator system used to lift fighters and animals into the arena.
Vatican Museums
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The Vatican Museums house one of the largest art collections in the world and lead to the Sistine Chapel, with Michelangelo's world-famous ceiling fresco and the Last Judgment.
Trevi Fountain
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The baroque 18th-century Trevi Fountain is the largest fountain in Rome, and tradition holds that throwing a coin over your left shoulder guarantees a return to Rome.
Pantheon
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The roughly 2000-year-old Pantheon is one of the best-preserved buildings of antiquity and still holds the largest unreinforced concrete dome in the world, with an open oculus through which rain falls directly onto the marble floor.